| Rank | Player | Date | Opponent | Blocks
|
|---|
| 1
| Khaleann Caron-Goudreau, Laval | Mar 9, 2019 | Ottawa | 10 |
| 2
| Alexandra Berry, Acadia | Mar 8, 2018 | Saskatchewan | 8 |
| 3
| Jessica Clemencon, Windsor | Mar 20, 2011 | Saskatchewan | 7 |
| 4
| Sarah Brodie, York | Mar 11, 2006 | McMaster | 6 |
| 5
| Dalyce Emmerson, Saskatchewan | Mar 19, 2016 | Saint Mary's | 6 |
| 6
| Denisha Haywood, Cape Breton | Mar 20, 2011 | StFX | 6 |
| 7
| Khaleann Caron-Goudreau, Laval | Mar 8, 2020 | UPEI | 5 |
| 8
| Jessica Clemencon, Windsor | Mar 16, 2013 | Calgary | 5 |
| 9
| Dalyce Emmerson, Saskatchewan | Mar 20, 2016 | Ryerson | 5 |
| 10
| Samantha Keltos, Brock | Mar 7, 2020 | UPEI | 5 |
| 11
| Nicki Schutz, Toronto | Mar 20, 2011 | Laurier | 5 |
| 12
| Claire Signatovich, Alberta | Mar 12, 2023 | Saint Mary's | 5 |
| 13
| Mariam Sylla, McGill | Mar 16, 2013 | UFV | 5 |
| 14
| Madalyn Weinert, Brock | Apr 2, 2022 | Ryerson | 5 |
| 15
| Sarah Wierks, UFV | Mar 14, 2014 | McGill | 5 |
| 16
| Khaleann Caron-Goudreau, Laval | Mar 10, 2019 | McMaster | 4 |
| 17
| Khaleann Caron-Goudreau, Laval | Mar 5, 2020 | Alberta | 4 |
| 18
| Alyssa Cerino, Carleton | Mar 8, 2018 | Calgary | 4 |
| 19
| Jessica Clarke, UBC | Mar 15, 2025 | Saskatchewan | 4 |
| 20
| Bobbi-Jo Colburn, Calgary | Mar 7, 2020 | Carleton | 4 |
| 21
| Julia Critchley, McMaster | Mar 11, 2007 | York | 4 |
| 22
| Carolina Del Santo, UPEI | Mar 5, 2020 | Ryerson | 4 |
| 23
| Dalyce Emmerson, Saskatchewan | Mar 15, 2014 | Saint Mary's | 4 |
| 24
| Dalyce Emmerson, Saskatchewan | Mar 12, 2015 | Alberta | 4 |
| 25
| Leanne Evans, UBC | Mar 9, 2007 | Dalhousie | 4 |
|
|
| Rank | Player | Date | Opponent | Blocks
|
|---|
| 26
| Leanne Evans, UBC | Mar 9, 2008 | Regina | 4 |
| 27
| Jane Gagne, Laval | Mar 9, 2018 | Acadia | 4 |
| 28
| Clara Gascoigne, Saint Mary's | Mar 8, 2024 | UFV | 4 |
| 29
| Reece Hall, Alberta | Mar 14, 2025 | Saint Mary's | 4 |
| 30
| Kirsten Jones, StFX | Mar 18, 2011 | Carleton | 4 |
| 31
| Jahlica Kirnon, Cape Breton | Mar 20, 2011 | StFX | 4 |
| 32
| Heather Lindsay, Carleton | Mar 11, 2018 | Saskatchewan | 4 |
| 33
| Christa Mancino, Laurier | Mar 18, 2011 | Saskatchewan | 4 |
| 34
| Katelyn Mangold, UNB | Mar 17, 2016 | McGill | 4 |
| 35
| Christina McCusker, Regina | Mar 10, 2017 | Victoria | 4 |
| 36
| Morgan McLaughlin, Simon Fraser | Mar 13, 2005 | Winnipeg | 4 |
| 37
| Kourtney Oss, Calgary
| Mar 5, 2026
| McGill | 4 |
| 38
| Claire Signatovich, Alberta | Mar 14, 2025 | Saint Mary's | 4 |
| 39
| Krista Singleton, Memorial | Mar 10, 2007 | Alberta | 4 |
| 40
| Mariam Sylla, McGill | Mar 12, 2015 | Saint Mary's | 4 |
| 41
| Stephanie Toxopeus, Cape Breton | Mar 6, 2009 | Regina | 4 |
| 42
| Madalyn Weinert, Brock | Apr 3, 2022 | Queen's | 4 |
| 43
| Julia Wilson, Simon Fraser | Mar 12, 2004 | UCCB | 4 |
| 44
| Kaitlyn Arbuthnot, Alberta | Mar 11, 2011 | StFX | 3 |
| 45
| Lucina Beaumont, Saint Mary's | Mar 11, 2023 | Carleton | 3 |
| 46
| Angela Bongomin, Regina | Mar 11, 2017 | Saskatchewan | 3 |
| 47
| Sophie-Anne Bouffard, Ottawa | Mar 13, 2025 | Laval | 3 |
| 48
| Christina Buttenham, McMaster | Mar 7, 2019 | Concordia | 3 |
| 49
| Christina Buttenham, McMaster | Mar 10, 2019 | Laval | 3 |
| 50
| Katie Butts, UNB
| Mar 5, 2026
| Carleton | 3 |
|